Research-grade reagents for Foot-and-mouth Disease Virus (FMDV) — a highly contagious picornavirus affecting cloven-hoofed animals with significant economic and agricultural impact. VP1 is the primary serotyping target and vaccine antigen mediating viral attachment and neutralization epitopes. We offer recombinant/polyclonal antibodies, recombinant proteins, validated for ELISA, Western blot, immunohistochemistry, and neutralization assays. Serotype-specific and cross-reactive reagents enable strain discrimination, viral diagnostics, vaccine efficacy evaluation, and mechanistic studies of immunity to FMDV across serotypes (A, O, C, SAT1, SAT2, SAT3, Asia1). RUO
Why Researchers Choose abinScience
Recombinant Antibodies (8) Epitope-mapped clones for ELISA, Western blot, and immunoassay development. Serotype-specific and cross-reactive clones suitable for diagnostic R&D, assay validation, and as reference standards for quality control in vaccine manufacturing.
Polyclonal Antibodies (13) Broad epitope recognition for Western blot and immunohistochemistry detection across multiple FMDV serotypes. Validated for ELISA, WB, IHC, and neutralization assays with high sensitivity for detecting viral antigens in tissue and cell culture samples.
Recombinant Proteins (17) His-tagged and Fc-tagged recombinant FMDV antigens (VP1, VP2, VP3, VP4, 2A, 3C, and other non-structural proteins) validated for SDS-PAGE, Western blot, and ELISA. Suitable as immunogens for antibody generation, coating antigens for serological assays, and assay standards for vaccine development and potency testing.
All products manufactured by AtaGenix Laboratories under ISO 9001 & ISO 13485 quality systems.
References
1. Knowles NJ, Samuel AR. Molecular epidemiology of foot-and-mouth disease virus. Virus Res. 2003;91(1):65-80. DOI
2. Grubman MJ, Baxt B. Foot-and-mouth disease. Clin Microbiol Rev. 2004;17(2):465-493. DOI
3. Belsham GJ. Foot-and-mouth disease virus capsid structure and function. Curr Top Microbiol Immunol. 2005;288:43-60. DOI
4. Domingo E, Escarmís C, Baranowski E, et al. Evolution of foot-and-mouth disease virus. Virus Res. 2003;91(1):47-63. DOI
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