Anti-FMDV VP1 Recombinant Antibody (4A2) (VK500033)

Name: Anti-FMDV VP1 Recombinant Antibody (4A2)
Brand: abinScience
SKU: VK500033
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK500033

Description

Anti-FMDV VP1 Recombinant Antibody (4A2) (VK500033) is a human monoclonal antibody detecting FMDV VP1 in ELISA, WB. Suitable for Foot-and-mouth disease virus (FMDV).

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Foot-and-mouth disease virus (FMDV)

Applications

ELISA, WB

Host species

Human

Clonality

Monoclonal

Isotype

IgG1, kappa

Clone ID

4A2

Target

Genome polyprotein, Leader protease, Lpro, 3.4.22.46, Capsid protein VP1, P1D, Virion protein 1

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P03309

RRID

Anti-FMDV Capsid protein VP1 Antibody (4A2) (abinScience Cat# VK500033, RRID:AB_3725869)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Genome polyprotein is a ~259 kDa protein. Autocatalytically cleaves itself from the polyprotein at the L/VP0 junction. Also cleaves the host translation initiation factors EIF4G1 and EIF4G3, in order to shut off the capped cellular mRNA transcription. Plays a role in counteracting host innate antiviral response using diverse mechanisms. Possesses a deubiquitinase activity acting on both 'Lys-48' and 'Lys-63'-linked polyubiquitin chains. In turn, inhibits the ubiquitination and subsequent activation of key signaling molecules of type I IFN response such as host RIGI, TBK1, TRAF3 and TRAF6.

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-FMDV Capsid protein VP1 Antibody (4A2).

References

Datasheet

Anti-FMDV VP1 Recombinant Antibody (4A2).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-FMDV VP1 Recombinant Antibody (4A2) (VK500033)

Overview

Images

References

Datasheet

SDS