

| Catalog No. | VK500043 | ||||||
|---|---|---|---|---|---|---|---|
| Description |
Anti-FMDV VP1 Recombinant Antibody (1E12#) (VK500043) is a human monoclonal antibody detecting FMDV VP1 in ELISA, WB. Suitable for Foot-and-mouth disease virus (FMDV).
Highlights
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| Species reactivity | Foot-and-mouth disease virus (FMDV) | ||||||
| Applications | ELISA, WB | ||||||
| Host species | Human | ||||||
| Clonality | Monoclonal | ||||||
| Isotype | IgG1, kappa | ||||||
| Clone ID | 1E12# | ||||||
| Target | Genome polyprotein, Leader protease, Lpro, 3.4.22.46, Capsid protein VP1, P1D, Virion protein 1 | ||||||
| Endotoxin level | < 10 EU/mg as determined by LAL method. | ||||||
| Purity | >95% as determined by SDS-PAGE. | ||||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||||
| Accession | P03309 | ||||||
| RRID | Anti-FMDV Capsid protein VP1 Antibody (1E12#) (abinScience Cat# VK500043, RRID:AB_3725870) |
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| Form | Liquid | ||||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| Background | Genome polyprotein is a ~259 kDa protein. Autocatalytically cleaves itself from the polyprotein at the L/VP0 junction. Also cleaves the host translation initiation factors EIF4G1 and EIF4G3, in order to shut off the capped cellular mRNA transcription. Plays a role in counteracting host innate antiviral response using diverse mechanisms. Possesses a deubiquitinase activity acting on both 'Lys-48' and 'Lys-63'-linked polyubiquitin chains. In turn, inhibits the ubiquitination and subsequent activation of key signaling molecules of type I IFN response such as host RIGI, TBK1, TRAF3 and TRAF6. | ||||||
| Note | For research use only. |

SDS-PAGE for Anti-FMDV Capsid protein VP1 Antibody (1E12#)
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