Canine Research Antibodies & Reagents

Browse Canine (Canis lupus familiaris) antibodies and recombinant proteins — species-validated reagents for veterinary medicine, comparative oncology, and translational research. The domestic dog genome (~2.4 Gb, ~20,700 protein-coding genes) shares high syntenic conservation with the human genome, and the unique breed structure — with long-range haplotype blocks and strong linkage disequilibrium created by centuries of artificial selection — makes the dog an exceptionally powerful model for genome-wide association studies (GWAS) of complex traits and diseases. Over 360 naturally occurring hereditary diseases have been characterized in dogs, many orthologous to human conditions including Duchenne muscular dystrophy, narcolepsy, retinal degenerative disorders, dilated cardiomyopathy, and breed-specific cancers (osteosarcoma, lymphoma, mast cell tumors, hemangiosarcoma). Our reagents support research across veterinary clinical diagnostics, comparative and translational oncology (canine tumors closely mimic human tumor biology, microenvironment, and therapeutic response), immune phenotyping (CD markers, cytokines, immunoglobulins), breed-specific genetic disorder investigation, and infectious disease studies (canine parvovirus, distemper, canine influenza). RUO

Species-Specific Validation Antibodies validated with confirmed reactivity to canine targets using species-appropriate positive controls from canine tissues, cell lines (MDCK, DH82), and serum samples.

Broad Target Coverage Canine immune markers (CD3, CD4, CD8, CD20, CD34, FoxP3), cytokines (canine IL-2, IL-6, IL-10, TNF-α, IFN-γ), immunoglobulins (IgG, IgA, IgM, IgE), oncology biomarkers, and infectious disease antigens.

Cross-Reactivity Data Detailed species cross-reactivity information provided on every product datasheet, enabling comparative studies across companion animal, veterinary, and human translational research contexts.

Multiple Applications Validated for WB, IHC, IF, ELISA, and FC across veterinary diagnostic, clinical pathology, comparative oncology, and pharmacokinetic research workflows.

Original Manufacturer In-house production under ISO 9001 & ISO 13485 quality systems — reliable supply, consistent lot-to-lot performance, and lot-specific CoA and validation data on every product page.

FAQs

How are your antibodies validated?

Every antibody is validated in its listed applications (WB, IHC, IF, ELISA, FC) with supporting images and data on the product page. We use positive and negative controls plus knockout/knockdown verification where available.

Do you offer conjugated antibodies?

Yes — HRP, AP, biotin, FITC, PE, APC, Alexa Fluor, and other fluorochrome conjugates are available. Custom conjugation services are also offered for bulk orders.

What species do your antibodies react with?

Most antibodies target human, mouse, and rat. Many show validated cross-reactivity with additional species including dog. Check the product datasheet for confirmed reactivity data.

What is your replacement policy?

If a product does not perform as described under recommended conditions, contact us within 30 days for replacement or credit. Our technical team will help troubleshoot first.

Can I get custom antibodies?

Yes — our parent company AtaGenix offers full custom antibody development from immunogen design through hybridoma screening and scale-up production.

All products manufactured by AtaGenix Laboratories under ISO 9001 & ISO 13485 quality systems.

References

1. Lindblad-Toh K, Wade CM, Mikkelsen TS, et al. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature. 2005;438(7069):803-819. DOI

2. Ostrander EA, Wayne RK. The canine genome. Genome Res. 2005;15(12):1706-1716. DOI

3. Karlsson EK, Lindblad-Toh K. Leader of the pack: gene mapping in dogs and other model organisms. Nat Rev Genet. 2008;9(9):713-725. DOI

4. Schoenebeck JJ, Ostrander EA. The genetics of canine skull shape variation. Genetics. 2013;193(2):317-325. DOI