InVivo Plus Anti-Human/Mouse/Rat CCL2/MCP-1 Antibody (2H5) (HY280019) is a armenian hamster monoclonal antibody detecting CCL2/MCP-1 in ELISA, FACS, Functional assay, Research in vivo. Suitable for Human, Mouse, Rat.
Highlights
●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.
Species reactivity
Human, Mouse, Rat
Applications
ELISA, FACS, Functional assay, Research in vivo
Host species
Armenian hamster
Clonality
Monoclonal
Isotype
IgG
Clone ID
2H5
Target
C-C motif chemokine 2, CCL2, HC11, MCAF, MCP-1, MCP1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2
Protein A/G purified from cell culture supernatant.
Accession
P13500, P10148, P14844
Form
Liquid
Storage buffer
0.01M PBS pH 7.4
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Product Usage Information
Application
Dilution
ELISA
1:2000-1:20000
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background
C-C motif chemokine 2 (HC11,MCP-1,MCP1,Monocyte chemotactic protein 1,Monocyte chemotactic and activating factor,Small-inducible cytokine A2,SCYA2,MCAF,Monocyte secretory protein JE,C-C motif chemokine 2,Monocyte chemoattractant protein 1,CCL2) is a ~11 kDa protein. Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
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7. Li, YS. et al. (1993) Molecular and cellular biochemistry 126, 61-8. PMID: 8107690
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