Anti-Human SRCAP Polyclonal Antibody (HP108014)

Name: Anti-Human SRCAP Polyclonal Antibody
Brand: abinScience
SKU: HP108014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HP108014

Description

Anti-Human SRCAP Polyclonal Antibody (HP108014) is a rabbit polyclonal antibody detecting SRCAP in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SRCAP (Lys2044-Thr2197).

Target

Helicase SRCAP, 3.6.4.-, Domino homolog 2, Snf2-related CBP activator, SRCAP, KIAA0309

Purification

Purified by antigen affinity column.

Accession

Q6ZRS2

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Chromatin remodeling protein SRCAP is a ~343 kDa protein. Acts both as a chromatin remodeler and transcription coregulator. Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes expression through chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription.

1. Ruhl, DD. et al. (2006) Biochemistry 45, 5671-7. PMID: 16634648

2. Wong, MM. et al. (2007) The Journal of biological chemistry 282, 26132-9. PMID: 17617668

3. Johnston, H. et al. (1999) The Journal of biological chemistry 274, 16370-6. PMID: 10347196

4. Monroy, MA. et al. (2001) The Journal of biological chemistry 276, 40721-6. PMID: 11522779

5. Monroy, MA. et al. (2003) Molecular endocrinology (Baltimore, Md.) 17, 2519-28. PMID: 14500758

6. Eissenberg, JC. et al. (2005) Molecular and cellular biology 25, 6559-69. PMID: 16024792

Note

For research use only.

Images

References

Datasheet

Anti-Human SRCAP Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SRCAP Polyclonal Antibody (HP108014)

Overview

Images

References

Datasheet

SDS

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