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Anti-Human ZC3H12D Polyclonal Antibody (HP358014)

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Overview
Catalog No.HP358014
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human ZC3H12D (Arg90-Pro231).
Target Probable ribonuclease ZC3H12D, MCP-induced protein 4, Zinc finger CCCH domain-containing protein 12D, TFL, Transformed follicular lymphoma, p34, MCPIP4, ZC3H12D, C6orf95
Purification Purified by antigen affinity column.
Accession A2A288
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Probable ribonuclease ZC3H12D is a ~58 kDa protein. May regulate cell growth likely by suppressing RB1 phosphorylation. May function as RNase and regulate the levels of target RNA species (Potential). In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages. Serve as a tumor suppressor in certain leukemia cells. Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation.

1. Minagawa, K. et al. (2009) Molecular cancer research : MCR 7, 880-9. PMID: 19531561
2. Huang, S. et al. (2015) The Journal of biological chemistry 290, 20782-20792. PMID: 26134560
3. Wang, M. et al. (2007) Cancer research 67, 93-9. PMID: 17210687
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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