Anti-CCHFV Glycoprotein Gn Polyclonal Antibody (VK608014)

Name: Anti-CCHFV Glycoprotein Gn Polyclonal Antibody
Brand: abinScience
SKU: VK608014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

VK608014

Description

Anti-CCHFV GP/Envelope glycoprotein Polyclonal Antibody (VK608014) is a rabbit polyclonal antibody detecting Glycoprotein N in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Crimean-Congo hemorrhagic fever virus (CCHFV)

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant CCHFV GP/Envelope glycoprotein (Ser520-Ser698).

Target

Envelopment polyprotein, M polyprotein, Mucin-like variable region, GP38, Glycoprotein N, Gn, 37 kDa protein, Glycoprotein G2, Non-Structural protein M, NSm, 15 kDa protein, Glycoprotein C, Gc, 75 kDa protein, Glycoprotein G1, GP

Purification

Purified by antigen affinity column.

Accession

Q8JSZ3

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Envelopment polyprotein (GP/Envelope glycoprotein) is a ~186 kDa protein. Plays a role in virion attachment to host receptor. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis Glycoprotein N probably locks the Gn-Gc complex in a prefusion state.

1. Xu, ZS. et al. (2024) Cell research 34, 140-150. PMID: 38182887

2. Simon, M. et al. (2009) The Journal of general virology 90, 210-5. PMID: 19088291

3. Mishra, AK. et al. (2022) Science (New York, N.Y.) 375, 104-109. PMID: 34793197

Note

For research use only.

Images

References

Datasheet

Anti-CCHFV Glycoprotein Gn Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-CCHFV Glycoprotein Gn Polyclonal Antibody (VK608014)

Overview

Images

References

Datasheet

SDS

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