Anti-Human SLC6A3 Polyclonal Antibody (HX986014)

Name: Anti-Human SLC6A3 Polyclonal Antibody
Brand: abinScience
SKU: HX986014
Price: 168 USD
Availability: InStock

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Datasheet
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Overview

Catalog No.

HX986014

Description

Anti-Human SLC6A3 Polyclonal Antibody (HX986014) is a rabbit polyclonal antibody detecting SLC6A3 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SLC6A3.

Target

Sodium-dependent dopamine transporter, DA transporter, DAT, Solute carrier family 6 member 3, SLC6A3, DAT1

Purification

Purified by antigen affinity column.

Accession

Q01959

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Sodium-dependent dopamine transporter (SLC6A3) is a ~68 kDa protein. Mediates sodium- and chloride-dependent transport of dopamine. Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling.

1. Wu, X. et al. (1999) Gene 233, 163-70. PMID: 10375632

2. Syringas, M. et al. (2000) Molecular pharmacology 58, 1404-11. PMID: 11093780

3. Giros, B. et al. (1992) Molecular pharmacology 42, 383-90. PMID: 1406597

4. Torres, GE. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 15650-5. PMID: 15505207

5. Kurian, MA. et al. (2009) The Journal of clinical investigation 119, 1595-603. PMID: 19478460

6. Li, Y. et al. (2024) Nature 632, 686-694. PMID: 39112701

7. Nielsen, JC. et al. (2024) Nature 632, 678-685. PMID: 39112703

8. Srivastava, DK. et al. (2024) Nature 632, 672-677. PMID: 39112705

9. Pristupa, ZB. et al. (1994) Molecular pharmacology 45, 125-35. PMID: 8302271

Note

For research use only.

Images

References

Datasheet

Anti-Human SLC6A3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SLC6A3 Polyclonal Antibody (HX986014)

Overview

Images

References

Datasheet

SDS

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