Anti-Mouse CD11b/ITGAM Polyclonal Antibody (MY474014)

Name: Anti-Mouse CD11b/ITGAM Polyclonal Antibody
Brand: abinScience
SKU: MY474014
Price: 96 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

MY474014

Description

Anti-Mouse CD11b/ITGAM Polyclonal Antibody (MY474014) is a rabbit polyclonal antibody detecting CD11b in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse CD11b/ITGAM (Gln615-Ala925).

Target

Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, CD11b, Itgam

Purification

Purified by antigen affinity column.

Accession

P05555

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Integrin alpha-M (CD11b/ITGAM) is a ~127 kDa protein. Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, and factor X. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

1. Wakselman, S. et al. (2008) The Journal of neuroscience : the official journal of the Society for Neuroscience 28, 8138-43. PMID: 18685038

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-ITGAM polyclonal antibody at 1ug/mL on various samples.
Lane 1: RAW264.7 cell lysate
Lane 2: Mouse spleen lysate