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Anti-Mouse CCL11/Eotaxin Recombinant Antibody (CAT-212) (MW762013)

Anti-Mouse CCL11/Eotaxin Recombinant Antibody (CAT-212)
Anti-Mouse CCL11/Eotaxin Recombinant Antibody (CAT-212)
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Overview
Catalog No.MW762013
Species reactivityHuman, Mouse
ApplicationsELISA, RIA, WB
Host speciesRat
IsotypeIgG1, kappa
Clone IDCAT-212
Clonality Monoclonal
Target Small-inducible cytokine A11, SCYA11, Eotaxin, CCL11, Eosinophil chemotactic protein, C-C motif chemokine 11, Eotaxin1, Eotaxin-1
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P48298
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Eotaxin (CCL11) is a ~10 kDa protein. Chemokine that plays a central role in both allergic and non-allergic inflammatory reactions by inducing the migration of different leukocyte types including eosinophils, basophils, macrophages and dendritic cells. Exerts its effects primarily by binding to the CCR3 receptor. Induces also chemotaxis of endothelial cells and promotes angiogenesis by activating the PI3K/Akt pathway.

1. Rothenberg, ME. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 8960-4. PMID: 7568052
2. Ganzalo, JA. et al. (1996) Immunity 4, 1-14. PMID: 8574847
Note For research use only.
Images
  • Anti-Mouse CCL11/Eotaxin Recombinant Antibody (CAT-212)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CCL11/Eotaxin Antibody (CAT-212)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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