

| Catalog No. | MW762022 |
|---|---|
| Description |
Recombinant Mouse CCL11/Eotaxin Protein, N-GST & C-His (MW762022) expressed in E. coli, spanning His24-Pro97. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | P48298 |
| Protein length | His24-Pro97 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Mus musculus (Mouse) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 36.62 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | C-C motif chemokine 11, CCL11, Eosinophil chemotactic protein, Eotaxin, SCYA11, Small-inducible cytokine A11 |
| Background | Eotaxin is a ~10 kDa protein. Chemokine that plays a central role in both allergic and non-allergic inflammatory reactions by inducing the migration of different leukocyte types including eosinophils, basophils, macrophages and dendritic cells. Exerts its effects primarily by binding to the CCR3 receptor. Induces also chemotaxis of endothelial cells and promotes angiogenesis by activating the PI3K/Akt pathway. 1. Rothenberg, ME. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 8960-4. PMID: 7568052 2. Ganzalo, JA. et al. (1996) Immunity 4, 1-14. PMID: 8574847 |
| Note | For research use only |


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