

| Catalog No. | MW762013 | ||||||
|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse | ||||||
| Applications | ELISA, RIA, WB | ||||||
| Host species | Rat | ||||||
| Isotype | IgG1, kappa | ||||||
| Clone ID | CAT-212 | ||||||
| Clonality | Monoclonal | ||||||
| Target | Small-inducible cytokine A11, SCYA11, Eotaxin, CCL11, Eosinophil chemotactic protein, C-C motif chemokine 11, Eotaxin1, Eotaxin-1 | ||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||
| Purity | >95% as determined by SDS-PAGE. | ||||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||||
| Accession | P48298 | ||||||
| Form | Liquid | ||||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
| ||||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| Background | Eotaxin (CCL11) is a ~10 kDa protein. Chemokine that plays a central role in both allergic and non-allergic inflammatory reactions by inducing the migration of different leukocyte types including eosinophils, basophils, macrophages and dendritic cells. Exerts its effects primarily by binding to the CCR3 receptor. Induces also chemotaxis of endothelial cells and promotes angiogenesis by activating the PI3K/Akt pathway. 1. Rothenberg, ME. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 8960-4. PMID: 7568052 2. Ganzalo, JA. et al. (1996) Immunity 4, 1-14. PMID: 8574847 | ||||||
| Note | For research use only. |

SDS-PAGE for Anti-Mouse CCL11/Eotaxin Antibody (CAT-212)


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