Anti-Human oxLDL Recombinant Antibody (SAA0552) (HP434023)

Name: Anti-Human oxLDL Recombinant Antibody (SAA0552)
Brand: abinScience
SKU: HP434023
Price: 126 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HP434023

Description

Anti-Human oxLDL Recombinant Antibody (SAA0552) (HP434023) is a mouse monoclonal antibody detecting oxLDL in ELISA, FCM, IHC. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, FCM, IHC

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone ID

SAA0552

Target

oxidised LDL, oxidised form of low-density lipoprotein (LDL), oxidised low-density lipoproteins, oxidized low-density lipoprotein, oxidized low-density lipoproteins, OxLDL

Endotoxin level

< 10 EU/mg

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

RRID

Anti-Human oxLDL Antibody (SAA0552) (abinScience Cat# HP434023, RRID:AB_3726076)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Adenosine 3', 5'-cyclic monophosphate (cAMP) is a key second messenger molecule in intracellular signal transduction. Monitoring cAMP levels is one of the most common ways to screen for agonists and antagonists of G protein–coupled receptors(GPCRs). Bioyeargene cAMP ELISA Kit is based on the competition between HRP-labeled cAMP and free cAMP for fixed amounts of mouse monoclonal anti-cAMP antibody(cAMP MAb) binding sites. Because the concentration of the HRP-labeled cAMP is held constant while the concentration of cAMP varies, the amount of HRP-labeled cAMP that is able to bind to the cAMP MAb will be inversely proportional to the concentration of cAMP in the well. This antigen-antibody complex binds to the goat anti-mouse IgG that has been previously attached to the well. The plate is washed to remove any unbound reagents and then developed. The ELISA typically displays an IC50(50% B/B0) of approximately 12 pmol/mL and a detection limit of approximately 0.15 pmol/mL.
• Sphingosine 1-phosphate: Lipid signaling in pathology and therapy., PMID:31624181
• Sphingosine-1-phosphate (S1P) in ovarian physiology and disease., PMID:31455516
• Sphingosine-1-phosphate (S1P) receptors: Promising drug targets for treating bone-related diseases., PMID:32155312
• Pancreatic Acinar Cells-Derived Sphingosine-1-Phosphate Contributes to Fibrosis of Chronic Pancreatitis via Inducing Autophagy and Activation of Pancreatic Stellate Cells., PMID:37634735
• Significance of sphingosine-1-phosphate in cardiovascular physiology and pathology., PMID:32278039
• Sphingosine 1-Phosphate (S1P)/ S1P Receptor Signaling and Mechanotransduction: Implications for Intrinsic Tissue Repair/Regeneration., PMID:31703256
• Sphingosine 1-phosphate (S1P) receptor modulators as an induction and maintenance therapy for ulcerative colitis: a systematic review and meta-analysis of randomized controlled trials., PMID:38153524
• S1P (Sphingosine-1-Phosphate)-Induced Vasodilation in Human Resistance Arterioles During Health and Disease., PMID:36070401
• Sphingosine 1-phosphate (S1P) signalling: Role in bone biology and potential therapeutic target for bone repair., PMID:28855094
• Sphingosine 1-phosphate signalling., PMID:24346695

Note

For research use only.

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