

| Catalog No. | HF743033 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Human TG/Thyroglobulin Nanobody (SAA1339) [SAA1339] (HF743033) is a alpaca monoclonal antibody detecting Thyroglobulin in ELISA, IF, IHC, RIA, SPR. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||
| Applications | ELISA, IF, IHC, RIA, SPR | ||||
| Host species | Alpaca | ||||
| Clonality | Monoclonal | ||||
| Isotype | VHH-8His-Cys-tag | ||||
| Clone ID | SAA1339 | ||||
| Target | Thyroglobulin, Tg, TG | ||||
| Endotoxin level | < 10 EU/mg as determined by LAL method. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Purified by Nickel column. | ||||
| Accession | P01266 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Thyroglobulin (TG) is a ~304 kDa protein. Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules. 1. Caputo, M. et al. (2007) Clinical endocrinology 67, 351-7. PMID: 17532758 2. Coscia, F. et al. (2020) Nature 578, 627-630. PMID: 32025030 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human TG/Thyroglobulin Nanobody (SAA1339)




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