Anti-Human IL-6 Recombinant Nanobody (SAA1289) (HY328023)

Name: Anti-Human IL-6 Recombinant Nanobody (SAA1289)
Brand: abinScience
SKU: HY328023
Price: 191 USD
Availability: InStock

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100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HY328023

Description

Anti-Human IL6 Nanobody (SAA1289) [SAA1289] (HY328023) is a alpaca monoclonal antibody detecting IL6 in ELISA, SPR. Suitable for Human.

Species reactivity

Human

Applications

ELISA, SPR, WB

Host species

Alpaca

Clonality

Monoclonal

Isotype

VHH-8His-Cys-tag

Clone ID

SAA1289

Tested applications

Target

B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, IFNB2, IL-6, IL6, Interferon beta-2, Interleukin-6

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

P05231

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Interleukin-6 (Hybridoma growth factor,BSF-2,IFN-beta-2,CDF,IL6,Interleukin-6,IL-6,B-cell stimulatory factor 2,Interferon beta-2,IFNB2,CTL differentiation factor) is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human IL6 Recombinant Nanobody (SAA1289)
Western blot

Western blot analysis was performed using anti-IL6 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human IL6 (Catalog No: HY328011)
Binding

SAA1289 binds with recombinant IL-6.

References

Datasheet

Anti-Human IL-6 Recombinant Nanobody (SAA1289).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human IL-6 Recombinant Nanobody (SAA1289) (HY328023)

Overview

Images

References

Datasheet

SDS