

| Catalog No. | HW387013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Human OPRK1 Nanobody (SAA1169) [SAA1169] (HW387013) is a alpaca monoclonal antibody detecting OPRK1 in ELISA. Suitable for Human.
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| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Alpaca | ||||
| Clonality | Monoclonal | ||||
| Isotype | VHH-8His-Cys-tag | ||||
| Clone ID | SAA1169 | ||||
| Target | OPRK, Kappa-type opioid receptor, KOR-1, K-OR-1, OPRK1 | ||||
| Endotoxin level | < 10 EU/mg as determined by LAL method. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Purified by Nickel column. | ||||
| Accession | P41145 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Kappa-type opioid receptor (OPRK1) is a ~42 kDa protein. G-protein coupled opioid receptor that functions as a receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as a receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human OPRK1 Nanobody (SAA1169)
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