

| Catalog No. | JN987020 |
|---|---|
| Description |
InVivoMAb Anti-Bordetella pertussis cyaA/Cyclolysin Antibody (Iv0145) [Iv0145] (JN987020) is a human monoclonal antibody detecting Bifunctional hemolysin/adenylate cyclase in ELISA.
|
| Species reactivity | Bordetella pertussis |
| Applications | ELISA |
| Host species | Human |
| Isotype | IgG1 |
| Clone ID | Iv0145 |
| Clonality | Monoclonal |
| Target | Bifunctional hemolysin/adenylate cyclase, AC-HLY, ACT, Cyclolysin, Calmodulin-sensitive adenylate cyclase, 4.6.1.1, ATP pyrophosphate-lyase, Adenylyl cyclase, Hemolysin, cya, cyaA, BP0760 |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Associated products | pH 7.4 Dilution Buffer |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P0DKX7 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | Bifunctional hemolysin/adenylate cyclase (cyaA/Cyclolysin) is a ~177 kDa protein. Bifunctional adenylate cyclase toxin-hemolysin that plays a crucial role in host colonization. It causes whooping cough by acting on mammalian cells by elevating cAMP-concentration and thus disrupts normal cell function. 1. Glaser, P. et al. (1991) The EMBO journal 10, 1683-8. PMID: 2050107 2. Glaser, P. et al. (1989) The EMBO journal 8, 967-72. PMID: 2542030 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for InVivoMAb Anti-Bordetella pertussis cyaA/Cyclolysin Antibody (Iv0145)
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