Anti-ZEBOV VP40/Matrix protein VP40 Recombinant Antibody (DSTL094) (VK783013)

Name: Anti-ZEBOV VP40/Matrix protein VP40 Recombinant Antibody (DSTL094)
Brand: abinScience
SKU: VK783013
Price: 191 USD
Availability: InStock

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1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK783013

Species reactivity

Zaire ebolavirus (strain Kikwit-95) (ZEBOV) (Zaire Ebola virus)

Applications

ELISA, WB

Host species

Human

Isotype

IgG

Clone ID

DSTL094

Clonality

Monoclonal

Target

VP40, Matrix protein VP40, Ebola VP40, eVP40, Membrane-associated protein VP40

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q77DJ6

RRID

Anti-ZEBOV VP40/Matrix protein VP40 Antibody (DSTL094) (abinScience Cat# VK783013, RRID:AB_3727249)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Matrix protein VP40 is a ~35 kDa protein. Plays an essential role virus particle assembly and budding. Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD6IP/ALIX, NEDD4 or TGS101. The interaction with host E3 ubiquitin ligase SMURF2 also facilitates virus budding. May play a role in immune cell dysfunction by being packaged into exosomes that can decrease the viability of recipient cells (via RNAi suppression and exosome-bystander apoptosis).

Note

For research use only.

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