Anti-Human ABCC1 Recombinant Antibody (SAA1629) (HW501013)

Name: Anti-Human ABCC1 Recombinant Antibody (SAA1629)
Brand: abinScience
SKU: HW501013
Price: 196 USD
Availability: InStock

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100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HW501013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1629

Clonality

Monoclonal

Target

Leukotriene C(4) transporter, ABCC1, MRP, Multidrug resistance-associated protein 1, MRP1, Glutathione-S-conjugate-translocating ATPase ABCC1, LTC4 transporter, ATP-binding cassette sub-family C member 1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P33527

RRID

Anti-Human ABCC1 Antibody (SAA1629) (abinScience Cat# HW501013, RRID:AB_3727390)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Multidrug resistance-associated protein 1 (ABCC1) is a ~171 kDa protein. Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation.

1. Sjölinder, M. et al. (1999) Journal of lipid research 40, 439-46. PMID: 10064732

2. Robbiani, DF. et al. (2000) Cell 103, 757-68. PMID: 11114332

3. Conseil, G. et al. (2006) The Journal of biological chemistry 281, 43-50. PMID: 16230346

4. Leier, I. et al. (1994) The Journal of biological chemistry 269, 27807-10. PMID: 7961706

5. Stride, BD. et al. (1997) Molecular pharmacology 52, 344-53. PMID: 9281595

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human ABCC1 Antibody (SAA1629)

References

Datasheet

Anti-Human ABCC1 Recombinant Antibody (SAA1629).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human ABCC1 Recombinant Antibody (SAA1629) (HW501013)

Overview

Images

References

Datasheet

SDS

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