Anti-Human RAB10 Recombinant Antibody (SAA1654) (HX991013)

Name: Anti-Human RAB10 Recombinant Antibody (SAA1654)
Brand: abinScience
SKU: HX991013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HX991013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1654

Clonality

Monoclonal

Target

Ras-related protein Rab-10, RAB10

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P61026

RRID

Anti-Human RAB10 Antibody (SAA1654) (abinScience Cat# HX991013, RRID:AB_3727415)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Ras-related protein Rab-10 (RAB10) is a ~22 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB10 is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Regulates, for instance, SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane. In parallel, RAB10 regulates the transport of TLR4, a toll-like receptor to the plasma membrane and therefore may be important for innate immune response.

1. Hutagalung, AH. et al. (2011) Physiological reviews 91, 119-49. PMID: 21248164

2. Babbey, CM. et al. (2006) Molecular biology of the cell 17, 3156-75. PMID: 16641372

3. English, AR. et al. (2013) Nature cell biology 15, 169-78. PMID: 23263280

4. Dhekne, HS. et al. (2018) eLife 7. PMID: 30398148

5. Lucken-Ardjomande Häsler, S. et al. (2020) The Journal of cell biology 219. PMID: 32344433

6. Eguchi, T. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E9115-E9124. PMID: 30209220

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human RAB10 Antibody (SAA1654)

References

Datasheet

Anti-Human RAB10 Recombinant Antibody (SAA1654).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human RAB10 Recombinant Antibody (SAA1654) (HX991013)

Overview

Images

References

Datasheet

SDS

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