

| Catalog No. | HV987013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Mouse | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | SAA1811 | ||||
| Clonality | Monoclonal | ||||
| Target | EMR2, EGF-like module receptor 2, ADGRE2, EGF-like module-containing mucin-like hormone receptor-like 2, Adhesion G protein-coupled receptor E2, CD312 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | Q9UHX3 | ||||
| RRID | Anti-Human CD312/ADGRE2/EMR2 Antibody (SAA1811) (abinScience Cat# HV987013, RRID:AB_3727573) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Adhesion G protein-coupled receptor E2 (CD312/ADGRE2) is a ~90 kDa protein. Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation. 1. Boyden, SE. et al. (2016) The New England journal of medicine 374, 656-63. PMID: 26841242 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human CD312/ADGRE2/EMR2 Antibody (SAA1811)
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