Anti-Human B2M/Beta-2-microglobulin Recombinant Nanobody (SAA1171) (HX250033)

Name: Anti-Human B2M/Beta-2-microglobulin Recombinant Nanobody (SAA1171)
Brand: abinScience
SKU: HX250033
Price: 126 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HX250033

Description

Anti-Human B2M/Beta-2-microglobulin Nanobody (SAA1171) [SAA1171] (HX250033) is a alpaca monoclonal antibody detecting Beta-2-microglobulin in ELISA, SPR. Suitable for Human.

Species reactivity

Human

Applications

ELISA, SPR

Host species

Alpaca

Isotype

VHH-8His-Cys-tag

Clone ID

SAA1171

Clonality

Monoclonal

Target

Beta-2-microglobulin, B2M

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

P61769

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Beta-2-microglobulin (B2M/β2M) is a ~13 kDa protein. Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.

1. Sreejit, G. et al. (2014) PLoS pathogens 10, e1004446. PMID: 25356553

Note

For research use only.

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