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InVivoMAb Anti-Nipah virus/NiV Prefusion Protein Antibody (2B12) (VK521050)

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InVivoMAb Anti-Nipah virus/NiV Prefusion Protein Antibody (2B12)

InVivoMAb Anti-Nipah virus/NiV Prefusion Protein Antibody (2B12)

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100ug
1mg

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Overview
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Datasheet

Overview

Catalog No.	VK521050
Description	InVivoMAb Anti-Nipah virus/NiV Prefusion Protein Antibody (2B12) [2B12] (VK521050) is a human monoclonal antibody detecting Fusion glycoprotein F0 in ELISA, Neutralization. Suitable for Nipah virus (NiV).
Species reactivity	Nipah virus (NiV)
Applications	ELISA, Neutralization
Host species	Human
Isotype	IgG1
Clone ID	2B12
Clonality	Monoclonal
Target	Fusion glycoprotein F0, Protein F, Fusion glycoprotein F2, Fusion glycoprotein F1, F, Prefusion Protein
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9IH63
RRID	InVivoMAb Anti-Nipah virus/NiV Prefusion Protein Antibody (2B12) (abinScience Cat# VK521050, RRID:AB_3728980)
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Fusion glycoprotein F0 (Prefusion Protein) is a ~60 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Nipah virus/NiV Prefusion Protein Antibody (2B12).

References

Datasheet

InVivoMAb Anti-Nipah virus/NiV Prefusion Protein Antibody (2B12).pdf

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InVivoMAb Anti-Nipah virus/NiV Prefusion Protein Antibody (2B12)