Anti-Nipah virus/NiV Fusion glycoprotein F1 Antibody (5G7) (VK521033)

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50ug
100ug
1mg

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Datasheet

Overview

Catalog No.

VK521033

Description

Anti-Nipah virus/NiV Fusion glycoprotein F1 Antibody (5G7) [5G7] (VK521033) is a human monoclonal antibody detecting Fusion glycoprotein F1 in IP, WB. Suitable for Nipah virus (NiV).

Species reactivity

Nipah virus (NiV)

Applications

IP, WB

Host species

Human

Isotype

IgG1

Clone ID

5G7

Clonality

Monoclonal

Target

Fusion glycoprotein, Protein F, Fusion glycoprotein F1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9IH63

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Fusion glycoprotein F0 (Fusion glycoprotein F1) is a ~60 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.

Note

For research use only.

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