InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19) (VK589050)

Name: InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19)
Brand: abinScience
SKU: VK589050
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	VK589050
Description	InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19) [1C19] (VK589050) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.
Species reactivity	Dengue virus type 1 (strain Nauru/West Pac/1974) (DENV-1), Dengue virus type 2 (strain Jamaica/1409/1983) (DENV-2), Dengue virus type 3 (strain Philippines/H87/1956) (DENV-3), Dengue virus type 4 (strain Dominica/814669/1981) (DENV-4)
Applications	ELISA, Neutralization
Host species	Human
Isotype	IgG1, kappa
Clone ID	1C19
Clonality	Monoclonal
Target	Genome polyprotein, Envelope protein E, DII-FL region
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P17763, P07564, P27915, P09866
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Genome polyprotein (Envelope protein E) is a ~378 kDa protein. Capsid protein C self-assembles to form an icosahedral capsid about 30 nm in diameter. The capsid encapsulates the genomic RNA (Probable). Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions. 1. Kuhn, RJ. et al. (2002) Cell 108, 717-25. PMID: 11893341 2. Sangiambut, S. et al. (2008) The Journal of general virology 89, 1254-1264. PMID: 18420804 3. Colpitts, TM. et al. (2011) PloS one 6, e24365. PMID: 21909430 4. Bhuvanakantham, R. et al. (2013) Cellular microbiology 15, 1688-706. PMID: 23522008
Note	For research use only. Not suitable for clinical or therapeutic use.

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Datasheet

InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19).pdf

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InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19) (VK589050)

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