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InVivo Plus Anti-Mouse CD4 Antibody (GK1.5) (MF998109)

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InVivo Plus Anti-Mouse CD4 Antibody (GK1.5)

InVivo Plus Anti-Mouse CD4 Antibody (GK1.5)

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Overview

Catalog No.	MF998109
Description	InVivo Plus Anti-Mouse CD4 Antibody (GK1.5) [GK1.5] (MF998109) is a rat monoclonal antibody detecting T-cell surface glycoprotein CD4 in in vivo CD4+ T cell depletion, FCM, WB. Suitable for Mouse. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Mouse
Applications	in vivo CD4+ T cell depletion, FCM, WB
Host species	Rat
Isotype	IgG2b
Clone ID	GK1.5
Clonality	Monoclonal
Target	T-cell surface glycoprotein CD4, T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, CD4
Endotoxin level	<1 EU/mg
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P06332
RRID	InVivo Plus Anti-Mouse CD4 Antibody (GK1.5) (abinScience Cat# MF998109, RRID:AB_3730113)
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	T-cell surface glycoprotein CD4 is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for InVivo Plus Anti-Mouse CD4 Antibody (GK1.5)

References

Datasheet

InVivo Plus Anti-Mouse CD4 Antibody (GK1.5).pdf

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InVivo Plus Anti-Mouse CD4 Antibody (GK1.5)