Anti-Nipah virus/NiV Fusion glycoprotein Recombinant Nanobody (DS90) (VK521053)

Name: Anti-Nipah virus/NiV Fusion glycoprotein Recombinant Nanobody (DS90)
Brand: abinScience
SKU: VK521053
Price: 191 USD
Availability: InStock

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100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

VK521053

Description

Anti-Nipah virus/NiV Fusion glycoprotein Nanobody (DS90) [DS90] (VK521053) is a alpaca monoclonal antibody detecting Fusion glycoprotein F in ELISA. Suitable for Nipah virus (NiV).

Species reactivity

Nipah virus (NiV)

Applications

ELISA

Host species

Alpaca

Isotype

VHH-His

Clone ID

DS90

Clonality

Monoclonal

Target

Fusion glycoprotein, Protein F, Fusion glycoprotein F

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

Q9IH63

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Fusion glycoprotein F0 is a ~60 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.

Note

For research use only.

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