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Anti-Human DCX Monoclonal Antibody (1A537) (HT416015)

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Anti-Human DCX Monoclonal Antibody (1A537)

Anti-Human DCX Monoclonal Antibody (1A537)

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Overview

Catalog No.	HT416015
Description	Anti-Human DCX Monoclonal Antibody (1A537) [1A537] (HT416015) is a mouse monoclonal antibody detecting DCX in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG
Clone ID	1A537
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant human DCX (Arg178-Gly276).
Target	Neuronal migration protein doublecortin, Doublin, Lissencephalin-X, Lis-X, DCX
Purification	Protein A/G purified from cell culture supernatant.
Accession	O43602
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Neuronal migration protein doublecortin (DCX) is a ~40 kDa protein. Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.
Note	For research use only.

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SDS-PAGE for Anti-Human DCX Monoclonal Antibody (1A537)

References

Datasheet

Anti-Human DCX Monoclonal Antibody (1A537).pdf

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Anti-Human DCX Monoclonal Antibody (1A537)