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Anti-Human CD7 Monoclonal Antibody (1A597) (HY302015)

Anti-Human CD7 Monoclonal Antibody (1A597)
Anti-Human CD7 Monoclonal Antibody (1A597)
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Overview
Catalog No.HY302015
Description
Anti-Human CD7 Monoclonal Antibody (1A597) [1A597] (HY302015) is a mouse monoclonal antibody detecting CD7 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesMouse
IsotypeIgG
Clone ID1A597
Clonality Monoclonal
Immunogen E. coli - derived recombinant human CD7 (Ala26-Pro180).
Target T-cell antigen CD7, GP40, T-cell leukemia antigen, T-cell surface antigen Leu-9, TP41, CD7, CD7
Purification Protein A/G purified from cell culture supernatant.
Accession P09564
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

T-cell antigen CD7 is a ~25 kDa protein. Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1. In turn, mediates the production of cytokines such as IL-2. On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels.

1. Rabinowich, H. et al. (1994) Journal of immunology (Baltimore, Md. : 1950) 152, 517-26. PMID: 7506726
2. Lyman, SD. et al. (2000) The Journal of biological chemistry 275, 3431-7. PMID: 10652336
3. Carrel, S. et al. (1991) European journal of immunology 21, 1195-200. PMID: 1709867
Note For research use only.
Images
  • Anti-Human CD7 Monoclonal Antibody (1A597)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD7 Monoclonal Antibody (1A597)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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