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Anti-Human NR5A1 Monoclonal Antibody (1A707) (HC154025)

Anti-Human NR5A1 Monoclonal Antibody (1A707)
Anti-Human NR5A1 Monoclonal Antibody (1A707)
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Overview
Catalog No.HC154025
Description
Anti-Human NR5A1 Monoclonal Antibody (1A707) [1A707] (HC154025) is a mouse monoclonal antibody detecting NR5A1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesMouse
IsotypeIgG
Clone ID1A707
Clonality Monoclonal
Immunogen E. coli - derived recombinant human NR5A1 (Glu225-Thr461).
Target Steroidogenic factor 1, SF-1, STF-1, hSF-1, Adrenal 4-binding protein, Fushi tarazu factor homolog 1, Nuclear receptor subfamily 5 group A member 1, Steroid hormone receptor Ad4BP, NR5A1
Purification Protein A/G purified from cell culture supernatant.
Accession Q13285
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Steroidogenic factor 1 (NR5A1) is a ~51 kDa protein. Transcriptional activator. Essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1.

1. Bashamboo, A. et al. (2016) Human molecular genetics 25, 3446-3453. PMID: 27378692
Note For research use only.
Images
  • Anti-Human NR5A1 Monoclonal Antibody (1A707)

    SDS-PAGE

    SDS-PAGE for Anti-Human NR5A1 Monoclonal Antibody (1A707)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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