

| Catalog No. | VK608044 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-CCHFV GP38 Polyclonal Antibody (VK608044) is a rabbit polyclonal antibody detecting GP38. Suitable for Crimean-Congo hemorrhagic fever virus.
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| Species reactivity | Crimean-Congo hemorrhagic fever virus (CCHFV) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant CCHFV GP38 (Asn248-Ser515). | ||||||||
| Target | 15 kDa protein, 37 kDa protein, 75 kDa protein, Envelopment polyprotein, GP, GP38, Gc, Glycoprotein C, Glycoprotein G1, Glycoprotein G2, Glycoprotein N, Gn, M polyprotein, Mucin-like variable region, NSm, Non-Structural protein M | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q8JSZ3 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Envelopment polyprotein (GP38) is a ~186 kDa protein. Plays a role in virion attachment to host receptor. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis Glycoprotein N probably locks the Gn-Gc complex in a prefusion state. 1. Xu, ZS. et al. (2024) Cell research 34, 140-150. PMID: 38182887 2. Simon, M. et al. (2009) The Journal of general virology 90, 210-5. PMID: 19088291 3. Mishra, AK. et al. (2022) Science (New York, N.Y.) 375, 104-109. PMID: 34793197 | ||||||||
| Note | For research use only |




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