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Anti-Human POLG2 Polyclonal Antibody (HD645014)

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Overview
Catalog No.HD645014
Description
Anti-Human POLG2 Polyclonal Antibody (HD645014) is a rabbit polyclonal antibody detecting POLG2. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human POLG2 (Arg182-Val485).
Target DNA polymerase gamma accessory 55 kDa subunit, DNA polymerase subunit gamma-2, MTPOLB, Mitochondrial DNA polymerase accessory subunit, MtPolB, POLG2, PolG-beta, p55
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q9UHN1
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

DNA polymerase subunit gamma-2 (POLG2) is a ~54 kDa protein. Accessory subunit of DNA polymerase gamma solely responsible for replication of mitochondrial DNA (mtDNA). Acts as an allosteric regulator of the holoenzyme activities. Enhances the polymerase activity and the processivity of POLG by increasing its interactions with the DNA template. Suppresses POLG exonucleolytic proofreading especially toward homopolymeric templates bearing mismatched termini. Binds to single-stranded DNA.

Note For research use only
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Anti-Human POLG2 Polyclonal Antibody

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