Anti-Human CEP63 Polyclonal Antibody (HD664014)

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Datasheet

Overview

Catalog No.

HD664014

Description

Anti-Human CEP63 Polyclonal Antibody (HD664014) is a rabbit polyclonal antibody detecting CEP63. Suitable for Human.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CEP63 (Met1-Ile309).

Target

CEP63, Centrosomal protein of 63 kDa, Cep63

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q96MT8

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Centrosomal protein of 63 kDa (CEP63) is a ~81 kDa protein. Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response.

1. Löffler, H. et al. (2011) Cancer research 71, 2129-39. PMID: 21406398

2. Sir, JH. et al. (2011) Nature genetics 43, 1147-53. PMID: 21983783

3. Kodani, A. et al. (2015) eLife 4. PMID: 26297806

4. Kodani, A. et al. (2022) EMBO reports 23, e52211. PMID: 35793002

5. Ling, H. et al. (2022) Oncogene 41, 4433-4445. PMID: 35989368

Note

For research use only

Images

References

Datasheet

Anti-Human CEP63 Polyclonal Antibody.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CEP63 Polyclonal Antibody (HD664014)

Overview

Images

References

Datasheet

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