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Anti-Human SLC6A2 NAT1 NET1 SLC6A5 Polyclonal Antibody (HD570014)

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Overview
Catalog No.HD570014
Description
Anti-Human SLC6A2 NAT1 NET1 SLC6A5 Polyclonal Antibody (HD570014) is a rabbit polyclonal antibody detecting SLC6A2. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human SLC6A2 NAT1 NET1 SLC6A5 (Phe167-Pro233&Ser363-Thr402&Pro570-Ile617).
Target NAT1, NET, NET1, Norepinephrine transporter, SLC6A2, SLC6A5, Sodium-dependent noradrenaline transporter, Solute carrier family 6 member 2
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P23975
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Sodium-dependent noradrenaline transporter (SLC6A2 NAT1 NET1 SLC6A5) is a ~69 kDa protein. Mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline), the primary signaling neurotransmitter in the autonomic sympathetic nervous system. Is responsible for norepinephrine re-uptake and clearance from the synaptic cleft, thus playing a crucial role in norepinephrine inactivation and homeostasis. Can also mediate sodium- and chloride-dependent transport of dopamine.

1. Pacholczyk, T. et al. (1991) Nature 350, 350-4. PMID: 2008212
2. Gu, H. et al. (1994) The Journal of biological chemistry 269, 7124-30. PMID: 8125921
3. Zhang, H. et al. (2024) Nature 630, 247-254. PMID: 38750358
4. Syringas, M. et al. (2000) Molecular pharmacology 58, 1404-11. PMID: 11093780
5. Brown, CR. et al. (2025) Journal of neurochemistry 169, e16241. PMID: 39395208
6. Tan, J. et al. (2024) Nature 632, 921-929. PMID: 39048818
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Volume
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human SLC6A2 NAT1 NET1 SLC6A5 Polyclonal Antibody

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