

| Catalog No. | MB650014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse CD13/ANPEP Polyclonal Antibody (MB650014) is a rabbit polyclonal antibody detecting Anpep. Suitable for Mouse.
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| Species reactivity | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Mouse CD13/ANPEP (Thr79-Glu285). | ||||||||
| Target | AP-M, AP-N, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, Anpep, CD13, EC:3.4.11.2, Lap-1, Lap1, Membrane protein p161, Microsomal aminopeptidase, mAPN | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P97449 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Aminopeptidase N (CD13/ANPEP) is a ~109 kDa protein. Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity. 1. Larsen, SL. et al. (1996) The Journal of experimental medicine 184, 183-9. PMID: 8691132 2. Fairweather, SJ. et al. (2012) The Biochemical journal 446, 135-48. PMID: 22677001 | ||||||||
| Note | For research use only |



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