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Anti-Human CAVIN1 Polyclonal Antibody (HP645024)

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Overview
Catalog No.HP645024
Description
Anti-Human CAVIN1 Polyclonal Antibody (HP645024) is a rabbit polyclonal antibody detecting CAVIN1. Suitable for Rat, Mouse, and Human.
Highlights
  • Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human CAVIN1 (Leu43-Val153).
Target CAVIN1, Caveolae-associated protein 1, Cavin-1, PTRF, Polymerase I and transcript release factor
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q6NZI2
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Caveolae-associated protein 1 (CAVIN1) is a ~43 kDa protein. Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues. Core component of the CAVIN complex which is essential for recruitment of the complex to the caveolae in presence of calveolin-1 (CAV1). Essential for normal oligomerization of CAV1. Promotes ribosomal transcriptional activity in response to metabolic challenges in the adipocytes and plays an important role in the formation of the ribosomal transcriptional loop.

1. Liu, L. et al. (2008) The Journal of biological chemistry 283, 4314-22. PMID: 18056712
2. Hill, MM. et al. (2008) Cell 132, 113-24. PMID: 18191225
3. Hayashi, YK. et al. (2009) The Journal of clinical investigation 119, 2623-33. PMID: 19726876
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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V₁ (Stock Vol.)
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Working Solution
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