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Anti-Human ATF6 Polyclonal Antibody (HB163044)

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Overview
Catalog No.HB163044
Description
Anti-Human ATF6 Polyclonal Antibody (HB163044) is a rabbit polyclonal antibody detecting ATF6. Suitable for Rat, Human, and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human ATF6 (Ala547-Gln670).
Target ATF6, ATF6-alpha, Activating transcription factor 6 alpha, Cyclic AMP-dependent transcription factor ATF-6 alpha, Processed cyclic AMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 alpha
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P18850
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Cyclic AMP-dependent transcription factor ATF-6 alpha (ATF6) is a ~74 kDa protein. Precursor of the transcription factor form (Processed cyclic AMP-dependent transcription factor ATF-6 alpha), which is embedded in the endoplasmic reticulum membrane. Endoplasmic reticulum stress promotes processing of this form, releasing the transcription factor form that translocates into the nucleus, where it activates transcription of genes involved in the unfolded protein response (UPR).

1. Haze, K. et al. (1999) Molecular biology of the cell 10, 3787-99. PMID: 10564271
2. Yoshida, H. et al. (2001) Molecular and cellular biology 21, 1239-48. PMID: 11158310
3. Yoshida, H. et al. (2001) Cell 107, 881-91. PMID: 11779464
Note For research use only
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Formula
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V₁ (Stock Vol.)
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Working Solution
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Anti-Human ATF6 Polyclonal Antibody

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