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Anti-Human MRPL12 Polyclonal Antibody (HC170014)

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Overview
Catalog No.HC170014
Description
Anti-Human MRPL12 Polyclonal Antibody (HC170014) is a rabbit polyclonal antibody detecting mitochondrial; L12mt; MRP-L12; 5c5-2; Mitochondrial large ribosomal subunit protein bL12m; MRPL12; MRPL7; RPML12. Suitable for Mouse and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human MRPL12 (His129-Glu198).
Target 39S ribosomal protein L12, mitochondrial; L12mt; MRP-L12; 5c5-2; Mitochondrial large ribosomal subunit protein bL12m; MRPL12; MRPL7; RPML12
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P52815
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Large ribosomal subunit protein bL12m (MRPL12) is a ~21 kDa protein. As a component of the mitochondrial large ribosomal subunit, plays a role in mitochondrial translation. When present in mitochondria as a free protein not associated with the ribosome, associates with mitochondrial RNA polymerase POLRMT to activate transcription. Required for POLRMT stability.

1. Serre, V. et al. (2013) Biochimica et biophysica acta 1832, 1304-12. PMID: 23603806
2. Surovtseva, YV. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 17921-6. PMID: 22003127
3. Nouws, J. et al. (2016) The Journal of biological chemistry 291, 989-97. PMID: 26586915
Note For research use only
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Datasheet
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Formula
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Anti-Human MRPL12 Polyclonal Antibody

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