Anti-Human/Mouse/Rat CD36/SR-B3 Recombinant Antibody (FA6-152) (HB030013) is a mouse monoclonal antibody detecting CD36/SR-B3 in ELISA, WB, FCM, IP, IF, in vivo. Suitable for Human.
Highlights
●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
Species reactivity
Human
Applications
ELISA, WB, FCM, IP, IF, in vivo
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone ID
FA6-152
Target
CD36, FAT, Fatty acid translocase, GP3B, GP4, GPIIIB, GPIV, Glycoprotein IIIb, Leukocyte differentiation antigen CD36, PAS IV, PAS-4, Platelet collagen receptor, Platelet glycoprotein 4, Platelet glycoprotein IV, Thrombospondin receptor
Endotoxin level
< 10 EU/mg
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P16671
Form
Liquid
Storage buffer
0.01M PBS pH 7.4.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application
Dilution
ELISA
1:2000-1:20000
WB
1:500-1:2000
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background
Platelet glycoprotein 4 (CD36) is a ~53 kDa protein. Multifunctional glycoprotein that acts as a receptor for a broad range of ligands. Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyloid-beta as well as of lipidic nature such as oxidized low-density lipoprotein (oxLDL), anionic phospholipids, long-chain fatty acids and bacterial diacylated lipopeptides. They are generally multivalent and can therefore engage multiple receptors simultaneously, the resulting formation of CD36 clusters initiates signal transduction and internalization of receptor-ligand complexes. The dependency on coreceptor signaling is strongly ligand specific. Cellular responses to these ligands are involved in angiogenesis, inflammatory response, fatty acid metabolism, taste and dietary fat processing in the intestine (Probable).
1. Smith, J. et al. (2008) The Journal of biological chemistry 283, 13578-85. PMID: 18353783
2. Mitchell, RW. et al. (2011) Journal of neurochemistry 117, 735-46. PMID: 21395585
3. Tran, TT. et al. (2011) The Journal of biological chemistry 286, 25201-10. PMID: 21610069
中文
English
한국어
日本語
Español
Français
Русский
