Anti-CD36 Polyclonal Antibody (HB030014)

Name: Anti-CD36 Polyclonal Antibody
Brand: abinScience
SKU: HB030014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

HB030014

Description

Anti-CD36 Polyclonal Antibody (HB030014) is a rabbit polyclonal antibody detecting CD36 in ELISA, IHC, WB. Suitable for Human and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD36 (Leu187-Asn428).

Target

CD36, FAT, GPIV, Fatty acid translocase, GP4, PAS IV, Leukocyte differentiation antigen CD36, Platelet collagen receptor, Platelet glycoprotein IV, Thrombospondin receptor, Platelet glycoprotein 4, GP3B, Glycoprotein IIIb, GPIIIB, PAS-4

Purification

Purified by antigen affinity column.

Accession

P16671

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Platelet glycoprotein 4 (CD36) is a ~53 kDa protein. Multifunctional glycoprotein that acts as a receptor for a broad range of ligands. Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyloid-beta as well as of lipidic nature such as oxidized low-density lipoprotein (oxLDL), anionic phospholipids, long-chain fatty acids and bacterial diacylated lipopeptides. They are generally multivalent and can therefore engage multiple receptors simultaneously, the resulting formation of CD36 clusters initiates signal transduction and internalization of receptor-ligand complexes. The dependency on coreceptor signaling is strongly ligand specific. Cellular responses to these ligands are involved in angiogenesis, inflammatory response, fatty acid metabolism, taste and dietary fat processing in the intestine (Probable).

1. Smith, J. et al. (2008) The Journal of biological chemistry 283, 13578-85. PMID: 18353783

2. Mitchell, RW. et al. (2011) Journal of neurochemistry 117, 735-46. PMID: 21395585

3. Tran, TT. et al. (2011) The Journal of biological chemistry 286, 25201-10. PMID: 21610069

4. Hao, JW. et al. (2020) Nature communications 11, 4765. PMID: 32958780

5. Masuda, D. et al. (2009) Journal of lipid research 50, 999-1011. PMID: 18753675

6. Keller, KL. et al. (2012) Obesity (Silver Spring, Md.) 20, 1066-73. PMID: 22240721

7. Mrizak, I. et al. (2015) The British journal of nutrition 113, 1330-7. PMID: 25822988

8. Stewart, CR. et al. (2010) Nature immunology 11, 155-61. PMID: 20037584

9. Triantafilou, M. et al. (2006) The Journal of biological chemistry 281, 31002-11. PMID: 16880211

Note

For research use only.

Images

References

Datasheet

Anti-CD36 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Anti-CD36 Polyclonal Antibody (HB030014)

Overview

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References

Datasheet

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