Anti-Human EMMPRIN/CD147 Reference Antibody (Metuzumab, RUO) (HW664056)

Name: Anti-Human EMMPRIN/CD147 Reference Antibody (Metuzumab, RUO)
Brand: abinScience
SKU: HW664056
Price: 370 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD): --

Spec:

100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HW664056

Description

Anti-Human EMMPRIN/CD147 Reference Antibody (Metuzumab, RUO) (HW664056) is a monoclonal antibody detecting EMMPRIN/CD147.

Species reactivity

Human

Applications

ELISA, FCM, Functional assay

Clonality

Monoclonal

Expression system

Mammalian cells

Nature

Recombinant

Target

5F7, BSG, Basigin, CD147, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, HAb18G, Hepatoma-associated antigen, Leukocyte activation antigen M6, OK blood group antigen, TCSF, Tumor cell-derived collagenase stimulatory factor

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt..

Background

Basigin (CD147/BSG) is a ~42 kDa protein. Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes.

1. Aït-Ali, N. et al. (2015) Cell 161, 817-32. PMID: 25957687

2. Redzic, JS. et al. (2011) Journal of molecular biology 411, 68-82. PMID: 21620857

Note

For research use only. Not suitable for clinical or therapeutic use.

Images

References

Datasheet

Anti-Human EMMPRIN/CD147 Reference Antibody (Metuzumab, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human EMMPRIN/CD147 Reference Antibody (Metuzumab, RUO) (HW664056)

Overview

Images

References

Datasheet

SDS