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Anti-HIV-1 gp120 Reference Antibody (PGDM1400, RUO) (VK617126)

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Overview
Catalog No.VK617126
Description
Anti-HIV-1 gp120 Reference Antibody (PGDM1400, RUO) (VK617126) is a human monoclonal antibody detecting gp120.
Species reactivityHuman immunodeficiency virus type 1 (HIV-1)
ApplicationsELISA, FACS, Functional assay
Host speciesHuman
ClonalityMonoclonal
IsotypeIgG
Clone IDPGDM1400
Target Env polyprotein, Envelope glycoprotein gp160, Glycoprotein 120, Glycoprotein 41, SU, Surface protein gp120, TM, Transmembrane protein gp41, env, gp120, gp41
Endotoxin level < 10 EU/mg
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession O12164
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt..
Background

Envelope glycoprotein gp160 (Envpolyprotein) is a ~97 kDa protein. Oligomerizes in the host endoplasmic reticulum into predominantly trimers. In a second time, gp160 transits in the host Golgi, where glycosylation is completed. The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.

Note For research use only.
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Formula
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