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Anti-HIV-1 Broadly Neutralizing Antibody (04_A06) (VK617073)

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Overview
Catalog No.VK617073
Description
Anti-HIV-1 Broadly Neutralizing Antibody (04_A06) (VK617073) is a human monoclonal antibody detecting gp120 in ELISA, Neutralization. Suitable for Human immunodeficiency virus type 1 (HIV-1.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman immunodeficiency virus type 1 (HIV-1
ApplicationsELISA, Neutralization
Host speciesHuman
ClonalityMonoclonal
IsotypeIgG
Clone ID04_A06
Target Env polyprotein, Envelope glycoprotein gp160, Glycoprotein 120, Glycoprotein 41, SU, Surface protein gp120, TM, Transmembrane protein gp41, env, gp120, gp41
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession O12164
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Envelope glycoprotein gp160 (Envpolyprotein) is a ~97 kDa protein. Oligomerizes in the host endoplasmic reticulum into predominantly trimers. In a second time, gp160 transits in the host Golgi, where glycosylation is completed. The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.

Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
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Working Solution
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