

| Catalog No. | HV212066 |
|---|---|
| Description |
Anti-Human BAFF/BLyS/TNFSF13B Reference Antibody (Rimizakibart, RUO) (HV212066) is a human monoclonal antibody detecting BAFF/BLyS/TNFSF13B.
|
| Species reactivity | Human |
| Applications | ELISA, FACS, Functional assay |
| Host species | Human |
| Clonality | Monoclonal |
| Isotype | IgG1, lambda2 |
| Target | B lymphocyte stimulator, B-cell-activating factor, BAFF, BLYS, BLyS, CD257, Dendritic cell-derived TNF-like molecule, TALL-1, TALL1, TNF- and APOL-related leukocyte expressed ligand 1, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, Tumor necrosis factor ligand superfamily member 13b, membrane form, Tumor necrosis factor ligand superfamily member 13b, soluble form, ZTNF4 |
| Endotoxin level | < 10 EU/mg |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | Q9Y275 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt.. |
| Alternate Names | CAS: 3081815-42-8 |
| Background | Tumor necrosis factor ligand superfamily member 13B (CD257/BAFF) is a ~31 kDa protein. Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. |
| Note | For research use only. |




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