Anti-LGALS8 Polyclonal Antibody (HT448014)

Name: Anti-LGALS8 Polyclonal Antibody
Brand: abinScience
SKU: HT448014
Price: 168 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.

HT448014

Description

Anti-LGALS8 Polyclonal Antibody (HT448014) is a rabbit polyclonal antibody detecting LGALS8 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human LGALS8 (Met2-Trp317).

Target

PCTA-1, Po66 carbohydrate-binding protein, Po66-CBP, Galectin-8, Gal-8, LGALS8, Prostate carcinoma tumor antigen 1

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

O00214

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Galectin-8 (GAL-8) is a ~35 kDa protein. Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses.

1. Thurston, TL. et al. (2012) Nature 482, 414-8. PMID: 22246324

2. Staring, J. et al. (2017) Nature 541, 412-416. PMID: 28077878

3. Ideo, H. et al. (2011) The Journal of biological chemistry 286, 11346-55. PMID: 21288902

Note

For research use only.

Images

References

Datasheet

Anti-LGALS8 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-LGALS8 Polyclonal Antibody (HT448014)

Overview

Images

References

Datasheet

SDS

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