Anti-CD32b/FCGR2B Polyclonal Antibody (HB103014)

Name: Anti-CD32b/FCGR2B Polyclonal Antibody
Brand: abinScience
SKU: HB103014
Price: 96 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB103014

Description

Anti-CD32b/FCGR2B Polyclonal Antibody (HB103014) is a rabbit polyclonal antibody detecting FCGR2B in ELISA, IHC, WB. Suitable for Human and Pan troglodytes.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD32b/FCGR2B (Ala46-Pro217).

Target

IGFR2, FCG2, Fc-gamma RII-b, CDw32, FcRII-b, IgG Fc receptor II-b, CD32, Fc-gamma-RIIb, Low affinity immunoglobulin gamma Fc region receptor II-b, FCGR2B

Purification

Purified by antigen affinity column.

Accession

P31994

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Low affinity immunoglobulin gamma Fc region receptor II-b (CD32b/FCGR2B) is a ~34 kDa protein. Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis.

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CD326 polyclonal antibody at 1μg/ml on various samples.
Lane 1: U937 cell lysate
Lane 2: Daudi cell lysate
Lane 3: Raji cell lysate
Lane 4: RAW264.7 cell lysate
Lane 5: K562 cell lysate
Lane 6: 293T cell lysate
Lane 7: Rat colon lysate
Lane 8: Rat liver lysate
Lane 9: Rat lung lysate