Goat Anti-Rabbit IgG H&L Polyclonal Antibody (TF690114)

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Overview

Catalog No.	TF690114
Description	Goat Anti-Rabbit IgG H&L Polyclonal Antibody (TF690114) is a goat polyclonal antibody in DB, ELISA, ICC, IHC, IP, WB. Suitable for Rabbit. Highlights ●Affinity Purified — Minimal background and high purity for reliable results. ●Multi-Application — Validated across multiple applications.
Species reactivity	Rabbit
Applications	DB, ELISA, ICC, IHC, IP, WB
Host species	Goat
Clonality	Polyclonal
Isotype	IgG
Tested applications	ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Purification	Purified by antigen affinity column.
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Immunoglobulin heavy constant gamma 4 (IgG4) is a ~43 kDa protein. Constant region of immunoglobulin (Ig) heavy chains. Igs are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound Igs serve as receptors, which upon binding to a specific antigen trigger the clonal expansion and differentiation of B lymphocytes into Ig-secreting plasma cells. Secreted Igs known as antibodies mediate the effector phase of humoral immunity by blocking the interaction of infectious antigens with cellular receptors (via the antigen-binding region) and eliciting effector mechanisms that lead to pathogen neutralization (via the constant region). The antigen-binding region is formed by the variable domain of one heavy chain paired with the variable domain of its associated light chain. 1. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170 2. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268 3. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414
Note	For research use only.