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Anti-Mouse CD8B//Lyt3 Recombinant Antibody (YTS156.7.7) (MY433107)

Anti-Mouse CD8B//Lyt3 Recombinant Antibody (YTS156.7.7)
Anti-Mouse CD8B//Lyt3 Recombinant Antibody (YTS156.7.7)
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Overview
Catalog No.MY433107
Species reactivityMouse
ApplicationsFCM
Host speciesRat
IsotypeIgG2b, kappa
Clone IDYTS156.7.7
Clonality Monoclonal
Target T-cell surface glycoprotein CD8 beta chain, Lymphocyte antigen 3, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein Lyt-3, CD8b, Cd8b1, Ly-3, Lyt-3, Lyt3, cd8
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P10300
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

T-cell surface glycoprotein CD8 beta chain (CD8b/Lyt3) is a ~24 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.

Note For research use only.
Images
  • Anti-Mouse CD8B//Lyt3 Recombinant Antibody (YTS156.7.7)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD8B//Lyt3 Antibody (YTS156.7.7)

References
Formula
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Formula
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V₁ (Stock Vol.)
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