

| Catalog No. | MY433107 |
|---|---|
| Species reactivity | Mouse |
| Applications | FCM |
| Host species | Rat |
| Isotype | IgG2b, kappa |
| Clone ID | YTS156.7.7 |
| Clonality | Monoclonal |
| Target | T-cell surface glycoprotein CD8 beta chain, Lymphocyte antigen 3, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein Lyt-3, CD8b, Cd8b1, Ly-3, Lyt-3, Lyt3, cd8 |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P10300 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | T-cell surface glycoprotein CD8 beta chain (CD8b/Lyt3) is a ~24 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |
| Note | For research use only. |

SDS-PAGE for Anti-Mouse CD8B//Lyt3 Antibody (YTS156.7.7)




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