

| Catalog No. | HW405107 |
|---|---|
| Species reactivity | Human |
| Applications | ELISA, FCM |
| Host species | Mouse |
| Isotype | VHH-mFc |
| Clone ID | SAA2103 |
| Clonality | Monoclonal |
| Target | Interferon gamma receptor 2, IFN-gamma receptor 2, IFN-gamma-R2, Interferon gamma receptor accessory factor 1, AF-1, Interferon gamma receptor beta-chain, IFN-gamma-R-beta, Interferon gamma transducer 1, IFNGR2, IFNGT1 |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P38484 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | Interferon gamma receptor 2 (IFNGR2) is a ~37 kDa protein. Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway. Required for signal transduction in contrast to other receptor subunit responsible for ligand binding. 1. Sakatsume, M. et al. (1995) The Journal of biological chemistry 270, 17528-34. PMID: 7615558 2. Kotenko, SV. et al. (1995) The Journal of biological chemistry 270, 20915-21. PMID: 7673114 3. Soh, J. et al. (1994) Cell 76, 793-802. PMID: 8124716 4. Rosenzweig, SD. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 3991-9. PMID: 15356148 |
| References | 1. Yang W, et al. Role of Azole Drugs in Promoting Fungal Cell Autophagy Revealed by an NIR Fluorescence-Based Theranostic Probe. Anal Chem. 2022 May 17;94(19):7092-7099. [HW405107] |
| Note | For research use only. |

SDS-PAGE for Anti-Human IFNGR2 Antibody (SAA2103)




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